Opioid Chemistry Stats
- Heroin
- Morphine
- Morphine
- Morphine Sulfate
- Morphine Hydrochloride
- Codeine
- Codeine
- Codeine Phosphate
- Codeine Sulfate
The information listed below uses some terms and abbreviations
that may be unfamiliar to you. They are listed in the following
table. If you have any questions, feel free to
contact us.
| Term | Description |
| brand name | This is the name that the drug is normally sold under. In many cases, there are any number of brand names and the band name may not refer to the drug itself, but rather a pill or other concoction that contains the drug. |
| name | This is the chemical or generic name of the drug. |
| formula | This is the chemical formula for the drug. |
| mol wt | Molecular weight. This is the number of grams that a mole of the drug weighs. |
| melts | This is the temperature at which the drug melts. Unless otherwise stated, this is under atmospheric pressure. |
| sol | This is the solubility of the drug in whatever liquid is listed--usually water. |
| LD50 | This is the lethal dose (LD) of the drug in whatever animal has been tested. The "50" indicates that this is the amount of the drug that caused half of the animals to die. The values given are mass of the drug per mass of the animal. So an LD50 of 100 mg/kg would mean for 100 mg of the drug for every kg the animal. LD50 is a good indication of how toxic a drug is, but note how much it changes from one species to another. There is a three-fold difference in the LD of heroin for mice versus monkeys. |
| IV, IM, SC | Intravenously, intramuscularly, subcutaneously |
Heroin
brand name Heroin name Diacetylmorphine Hydrochloride formula C21H23NO5HCl mol wt 369.42 melts 243-244oC sol 1 g / 2 g H2O LD50 mice 22 mg/kg (IV) LD50 monkeys 7 mg/kg (IV)
Morphine
formula C17H19NO3 mol wt 285.34 Fraction of Opium 9% - 14%
Morphine Sulfate
formula C34H40N2O10S mol wt 668.77 melts ~200oC sol 1 g / 15.5 g H2O (25oC) 1 g / 0.7 g H2O (80oC)
Morphine Hydrochloride
formula C17H20ClNO3HCl mol wt 321.80 melts ~200oC sol 1 g / 17.5 g H2O (25oC) 1 g / 0.5 g H2O (80oC) LD50 mice 226-318 mg/kg (IV)
Codeine
formula C18H21NO3 mol wt 299.37 Fraction of Opium 0.7% - 2.5% melts 154 - 156oC sol 1 g / 120 ml H2O (25oC) 1 g / 60 ml H2O (80oC) LD50 mice 300 mg/kg (SC)
Codeine Phosphate
formula C18H24NO7P mol wt 397.36 melts 154 - 156oC sol 1 g / 2.3 ml H2O (25oC) 1 g / 0.5 ml H2O (80oC)
Notes: Codeine in pill form is usually found in this
phosphate form.
Codeine Sulfate
formula C36H44N2O10S mol wt 696.82 sol 1 g / 30 ml H2O (25oC) 1 g / 6.5 ml H2O (80oC)
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