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Making Vicodin Less Toxic

Editor's Note: The information listed below (as simple and painless as it is), is most likely illegal in the United States and also possibly less oppressive nations. My feeling is always that if you are doing such chemistry for the purpose of detox, you are probably okay (even if not technically so). If you are doing it to get high, you are certainly running afoul of the law.

I was in jail with this kid who had been there for a week waiting for arraignment because he couldn't afford bail. He was in for faking scripts for Vicodin--an illegal act he had committed almost daily for the previous four years without detection from law enforcement.

He told me he was doing 40 Vicodin per day. Vicodin consists of two parts: 5 mg of hydrocodone and 500 mg of acetaminophen. Let's see now, 40 times 500 mg is: 20 grams of acetaminophen per day! Acetaminophen is toxic to the liver. I'd rather expose my liver to Hepatitis C than this kind of daily bombardment.

What of the 200 mg of hydrocodone this young man was ingesting daily? It's nothing. About the worst you can say is that he was addicted to the stuff. But his withdrawal was not very bad; this quantity of hydrocodone is equivalent to a 25 mg heroin habit--about $5 per day.

Despite what the authorities tell you, drugs are not legal or illegal based upon their danger. This kid was rotting in jail, not because of what he was doing to hurt himself (acetaminophen) but rather because of what he was doing to get high (hydrocodone). The government doesn't want you taking control over your own life and recreation.

But you can have your hydrocodone and keep your liver too. In fact, it's really easy. Acetaminophen is not very water soluble and hydrocodone is. Crush your Vicodin with a mortar and pestle and put it into some kind of vial with water--a test tube works really well for this. Mix the solution for a few minutes. Let the solution settle for a few minutes and strain it. Discard the particulate matter. Voila! The solution is non-toxic hydrocodone. Now all you have to worry about is The Law.

by Dr. H
© 2001


HEROIN helper recently received the following email:

I found on the HEROIN helper website a simple method to remove acetaminophen from Vicodin, since the Tylenol is really the more dangerous of the two ingredients in the pills. If this method is used, one would be left with a liquid form of the hydrocodone. What would be the best way to take it then? Most importantly, would the solution be safe for injecting? I ask because I read somewhere that some meds are dangerous to try this with, some even deadly.

Sometime in the near future, HEROIN helper will deal with this issue in more detail. For now, it is necessary to add a clarification to this article.

It is known that codeine administered intravenously at a large enough concentration (which can be quite small) can cause pulmonary edema. This is the swelling of lung tissue and can result in death. We have no information on IV hydrocodone. But hydrocodone acts, in many ways, like codeine. As a result, until we learn something to the contrary, the official HEROIN helper position is

Don't IV Hydrocodone

by Dr. H © 2001


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